Transcutaneous auricular vagus nerve stimulation in treating major depressive disorder

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Transcutaneous Vagus Nerve Stimulation Modulates Default Mode Network in Major Depressive Disorder.

BACKGROUND Depression is the most common form of mental disorder in community and health care settings and current treatments are far from satisfactory. Vagus nerve stimulation (VNS) is a Food and Drug Administration approved somatic treatment for treatment-resistant depression. However, the involvement of surgery has limited VNS only to patients who have failed to respond to multiple treatment...

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Transcutaneous Vagus Nerve Stimulation (taVNS) for Major Depressive Disorder: An Open Label Proof-of-Concept Trial.

Despite recent advances in pharmacological treatments, Major Depressive Disorder (MDD) remains an incapacitating psychiatric condition with increasing prevalence and economic burden [1]. New therapeutical strategies such as vagus nerve stimulation (VNS) are being studied [2]. Different brain sites can be modulated by using electrical currents, which can theoretically restore balance to impaired...

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Treating Depression with Transcutaneous Auricular Vagus Nerve Stimulation: State of the Art and Future Perspectives

Depression is a highly prevalent disorder, and its treatment is far from satisfactory. There is an urgent need to develop a new treatment for depression. Although still at its early stage, transcutaneous auricular vagus nerve stimulation (taVNS) has shown promising potential for treating depression. In this article, we first summarize the results of clinical studies on the treatment effect of t...

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Transcutaneous Auricular Vagus Nerve Stimulation Triggers Melatonin Secretion and Is Antidepressive in Zucker Diabetic Fatty Rats

Decreased circulating melatonin is implicated in depression. We recently found that Zucker diabetic fatty rats (ZDF, fa/fa) develop depression-like behaviors and that transcutaneous auricular vagus nerve stimulation (taVNS) is antidepressive in ZDF rats. Here we studied whether the ZDF rats could be used as a depression rodent model and whether the antidepressive effect of taVNS is mediated thr...

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The Effect of Transcutaneous Auricular Vagus Nerve Stimulation on Impaired Glucose Tolerance: A Pilot Randomized Study

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ژورنال

عنوان ژورنال: Medicine

سال: 2018

ISSN: 0025-7974,1536-5964

DOI: 10.1097/md.0000000000013845